Abstract
Abstract Enantiomers of 6,7-dihydroxy-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride were separated via diastereoisomeric salt formation using optically active tartaric acid, by inclusion-complex formation using water-soluble cyclodextrin polymer, and by inclusion chromatography on β-cyclodextrin bead polymer. On a microscale, the chromatographic resolution has significant advantages over the traditional methods.
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