Abstract
Background : HIV,HBV,& HCV is preventable transmitted disease, can accurately & correctly analyse by Elisa ,a superior method than rapid screening of blood units & its components. Aim : To see the positive results shown by Elisa method is positive by rapid or not. By this the superiority of method can be decided for screening of blood units in blood bank. Method : Out of 3650 blood units a sample of 50 elisa reactives were retested by Rapid method & results are analysed & compared. Only the higher Optical density gives positive result by rapid. Lower Optical density were not detected by rapid method, carry the risk of transmission to recipient. Result : The result of Elisa is not parallel to rapid test. Many samples reactive by Elisa were not detected positive by rapid due to low OD. Conclusion : Study shown that Rapid testing of samples for HIV, HBV& HCV are inferior to Elisa, Which is a gold standard for screening of blood donors in blood banks. DOI: 10.21276/AABS.1450
Highlights
(3) Screening of blood donors/blood units is done in almost every blood bank facility for viral marker like HIV,HBV & HCV before the blood units/components are transfused to prevent TTIs
Inspite the marked improvement in safety of blood donations, viruses, bacterias remain the most transmitted infection passed on from donor to recipient through transfusion.(4) The greatest risk are donations given in infectious window period (WP),which is the time between the development of infectious viraemia & reactivity by routine serological or nucleic acid technology(NAT)donor screening test
In case of HBV out of 36 cases, only 28 cases (77.7%) positive by rapid method, & 8 cases(22.2%) not detected positive
Summary
Blood transfusion services is a life saving vital part of modern health care system(1) worldwide TTIs still remain a major public health problem in many developing countries, mainly due to resourced facility, lack of staff. (2) Blood transmitted infections involves pathogenic viruses are most prominent in transfusion medicine. (3) Screening of blood donors/blood units is done in almost every blood bank facility for viral marker like HIV,HBV & HCV before the blood units/components are transfused to prevent TTIs. (3) Screening of blood donors/blood units is done in almost every blood bank facility for viral marker like HIV,HBV & HCV before the blood units/components are transfused to prevent TTIs. With every units of blood there is 1% chance of TTIs. Inspite the marked improvement in safety of blood donations, viruses, bacterias remain the most transmitted infection passed on from donor to recipient through transfusion.(4) The greatest risk are donations given in infectious window period (WP),which is the time between the development of infectious viraemia & reactivity by routine serological or nucleic acid technology(NAT)donor screening test. Conclusion: Study shown that Rapid testing of samples for HIV, HBV& HCV are inferior to Elisa, Which is a gold standard for screening of blood donors in blood banks
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