Abstract
Comparison of electroconvulsive therapy, buprenorphine and methadone in the management of methamphetamine dependency and withdrawal craving
Highlights
The problem of alcohol dependence, as well as the repercussion of alcohol consumption is one of the most dramatic and socially relevant problems for modern society[1]
These results support our hypothesis that tolerance to the effect of ethanol is mainly related to its influence on the activity of gastric receptors, which mediates a variety of changes in the central nervous mechanisms
One of these problems is the problem of tolerance to different effects of ethanol
Summary
The problem of alcohol dependence, as well as the repercussion of alco- Accepted Date: November 04, 2016 hol consumption is one of the most dramatic and socially relevant problems for modern Published Date: November 08, 2016 society. Aims: Studying the development of tolerance to anxiolytic, psycho stimulant and analgesic effects of ethanol upon repeated intragastric administration of ethanol in the same dose, but in various volumes. Methods: Male Wistar rats were treated with ethanol at the same dose (2 g/kg), but in various concentrations (40 ml/kg 5%, 15,5 ml/kg 13%, and 5 ml/kg 40% v/v). The level of anxiety and locomotor activity of animals were evaluated in the elevated plus. The analgesic effect of ethanol was studied in the hot plate test
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