Comparison of effects of percutaneous radiofrequency ablation and laparoscopic liver cancer resection on small hepatocellular carcinoma

Abstract

Objective To compare the effects of percutaneous radiofrequency ablation and laparoscopic hepatectomy on small hepatocellular carcinoma. Methods A total of 60 patients with small hepatocellular carcinoma treated in the 988 Hospital of the Joint service of the People’s Liberation Army from January 2016 to December 2018 were randomly selected and divided into two groups by random number table method. Thirty cases in ablation group were treated by percutaneous radiofrequency ablation, and 30 cases in endoscopic group were treated by laparoscopic hepatectomy. Percutaneous radiofrequency ablation was performed in the ablation group, and laparoscopic liver cancer resection was performed in the endoscopic group. The liver function indexes, tumor markers, complications and postoperative survival of the two groups were compared. Results The alanine aminotransferase was (37.94±5.46)U/L, and the aspartate aminotransferase was (40.73 ± 5.55)U/L in the ablation group at 1 month after operation, which were higher than (32.32±4.48)U/L, (35.24±5.48)U/L in the endoscopic group (P 0.05). Conclusions Both regimens can be used in the treatment of small hepatocellular carcinoma, by which the survival time of the patients can be prolonged. Radiofrequency ablation has less postoperative complications, but would impair a certain function of liver in the short term. Key words: Laparoscopes; Small hepatocellular carcinoma; Percutaneous radiofrequency ablation