Abstract

A suggestion that there might be antigens on bird sperm which were also found preferentially on either X-bearing or V-bearing mammalian sperm was investigated. Antisera to bird (cock) sperm were raised in rabbits and their effects on rabbit sperm compared with those of control sera from nonimmunized rabbits, using both in vitro and in vivo tests. The antisera showed no strong anti-rabbit sperm activity in vitro, indicating that cock sperm and rabbit sperm were in general antigenically dissimilar, but a significant difference was found between the sex ratios of offspring resulting from inseminating does with rabbit semen + anti-cock sperm sera and those resulting from insemination with rabbit semen + control sera, which might reflect a small degree of antigenic similarity between cock sperm and one genotype of rabbit sperm.

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