Comparison of effects of different labor analgesia regimens on perinatal mental state of parturients

Abstract

Objective To compare the effects of sufentanil mixed with ropivacaine and ropivacaine alone for peripartum analgesia on perinatal mental state of parturients. Methods Three hundred and eighty-nine primiparous acquiring labor analgesia in our hospital from April 2016 to April 2019, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ, at ≥37 weeks of gestation, aged 25-45 yr, were divided into 2 groups using a random number table method: ropivacaine group (R group, n=193) and ropivacaine mixed with sufentanil group (RS group, n=196). Epidural labor analgesia was performed with 1.5% ropivacaine in group R. Epidural labor analgesia was performed with 1% ropivacaine mixed with 0.5 μg/ml sufentanil in group RS.The Edinburgh depression scale (EPDS), multidimensional social support perception scale (MSPSS) and breast-feeding self-brief scale (BSES) were used to evaluate the maternal psychological status at 30 min after labor analgesia induction and 42 days after delivery. Results One hundred and sixty-one patients completed the study in group RS and 157 patients in group R. Compared with group RS, the EPDS score was significantly decreased, and the BSES score was increased at 42 days after delivery (P 0.05). Conclusion Compared with epidural labor analgesia with ropivacaine, epidural labor analgesia with sufentanil mixed with ropivacaine has a marked adverse effect on the perinatal mental state of parturients. Key words: Analgesia, obstetrical; Depression, postpartum