Abstract

In this paper, we analyze the dynamical behavior of the delayed fractional-order tumor model with Caputo sense and discretized conformable fractional-order tumor model. The model is constituted with the group of nonlinear differential equations having effector and tumor cells. First of all, stability and bifurcation analysis of the delayed fractional-order tumor model in the sense of Caputo fractional derivative is studied, and the existence of Hopf bifurcation depending on the time delay parameter is proved by using center manifold and bifurcation theory. Applying the discretization process based on using the piecewise constant arguments to the conformable version of the model gives a two-dimensional discrete system. Stability and Neimark–Sacker bifurcation analysis of the discrete system are demonstrated using the Schur-Cohn criterion and projection method. This study reveals that the delay parameterτin the model with Caputo fractional derivative and the discretization parameterhin the discrete-time conformable fractional-order model have similar effects on the dynamical behavior of corresponding systems. Moreover, the effect of the order of fractional derivative on the dynamical behavior of the systems is discussed. Finally, all results obtained are interpreted biologically, and numerical simulations are presented to illustrate and support theoretical results.

Highlights

  • Cancer is a very complex system as it integrates around two hundred different diseases with different characteristics and so, it is the leading cause of mortality worldwide

  • We add an extra delay parameter to model (1.2), and we consider the fractional form of this model with both Caputo and conformable sense, which are given as model (1.5) and model (1.7), respectively

  • We note that we use piecewise constant arguments in model (1.7) instead of the delay parameter in model (1.5)

Read more

Summary

Introduction

Cancer is a very complex system as it integrates around two hundred different diseases with different characteristics and so, it is the leading cause of mortality worldwide.

Objectives
Results
Conclusion

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.