Abstract
OBJECTIVES: To compare the angiographic and clinical outcomes in patients who have undergone peripheral artery intervention using either drug eluting stents (DES) or bare metal stents (BMS). METHODS: A meta-analysis of randomized studies that compare DES and BMS in patients with femoropopliteal occlusive artery disease. RESULTS: Five clinical trials met the inclusion criteria. Results showed that using DES yielded a higher arterial patency rate (RR 1.41; 95% CI 1.23-1.61), reduced restenosis rate (RR 0.46; 95% CI 0.33-0.63), and had a lesser tendency for repeat revascularization (RR 0.29; 95% CI 0.16-0.51) compared with BMS. However, no statistical significance was noted between the two interventions in terms of mortality rate (RR 0.93; 95% CI 0.47-1.83) and ankle brachial index score (mean difference of 0.06; 95% CI 0.02-0.09). KEY WORDS: Peripheral artery disease, peripheral artery intervention, drug eluting stents, bare metal stents, femoropopliteal occlusive disease
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