Abstract
The efficiency of synapses of the perforant path located on terminals of apical dendrites of CA1 and CA3 neurons was investigated in sections of the guinea pig hippocampus in vitro. Neurons of both areas were shown to respond to stimulation of the perforant path by action potential generation. Responses of most CA1 neurons appeared to repetitive stimulation with a frequency of up to 30–80/sec. Neurons in area CA3 respond only to low-frequency stimulation (under 5/sec). Posttetanic potentiation of responses to stimulation of the perforant path was found in both areas of the hippocampus.
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