Abstract

BackgroundThis study aimed to compare the clinical efficacy of digital subtraction angiography (DSA) combined arterial thrombectomy versus simple arterial thrombectomy in the treatment of acute lower limb ischemia (ALI).MethodsThis retrospective cohort study collected the clinical data from 124 patients (128 affected lower limbs) with ALI who underwent emergency surgery from March 2010 to November 2019. Patients were consecutively divided into Group A and Group B. Patients in Group A underwent simple arterial thrombectomy via the Fogarty catheterization. Patients in Group B underwent arterial thrombectomy, and the DSA was performed during the surgery. The differences in the success rate of primary surgery, the second intervention rate, and the amputation/mortality rate within 30-days after surgery were compared.ResultsIn Group A, 4 of 70 limbs (5.7%) were amputated, 54 of 70 limbs (77.1%) had improved blood flow, 14 of 70 limbs (20.0%) received a second intervention, and 3 of 68 patients (4.4%) died within 30 days. In Group B, 1 of 58 limbs (1.7%) was amputated, 56 of 58 limbs (96.6%) had improved blood flow, 3 of 58 limbs (5.2%) received a second intervention, and 2 of 56 patients (3.5%) died within 30-days. The success rate of primary surgery, the second intervention rate, and the amputation rate of Group B were significantly lower than Group A (P < 0.05).ConclusionArterial thrombectomy combined with DSA may effectively improve the clinical efficacy of patients with ALI.

Highlights

  • This study aimed to compare the clinical efficacy of digital subtraction angiography (DSA) combined arterial thrombectomy versus simple arterial thrombectomy in the treatment of acute lower limb ischemia (ALI)

  • We selected the patients with ALI who underwent DSA combined arterial thrombectomy or simple arterial thrombectomy from March 2010 to November 2019 in our hospital

  • We collected the clinical data from 124 patients with ALI who underwent DSA combined arterial thrombectomy or simple arterial thrombectomy from March 2010 to November 2019 in our hospital

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Summary

Introduction

This study aimed to compare the clinical efficacy of digital subtraction angiography (DSA) combined arterial thrombectomy versus simple arterial thrombectomy in the treatment of acute lower limb ischemia (ALI). Acute lower limb ischemia (ALI) is the sudden decrease in blood perfusion of lower limbs due to many causes, such as embolic and thrombotic vascular occlusion [1]. Along with the popularity of the digital subtraction angiography (DSA) hybrid operating room, more and more cases receive surgical treatment under DSA at present, which obviously increases the success rate of ALI treatment [8]. We selected the patients with ALI who underwent DSA combined arterial thrombectomy or simple arterial thrombectomy from March 2010 to November 2019 in our hospital.

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