Abstract
.Significance: Hyperspectral and multispectral imaging (HMSI) in medical applications provides information about the physiology, morphology, and composition of tissues and organs. The use of these technologies enables the evaluation of biological objects and can potentially be applied as an objective assessment tool for medical professionals.Aim: Our study investigates HMSI systems for their usability in medical applications.Approach: Four HMSI systems (one hyperspectral pushbroom camera and three multispectral snapshot cameras) were examined and a spectrometer was used as a reference system, which was initially validated with a standardized color chart. The spectral accuracy of the cameras reproducing chemical properties of different biological objects (porcine blood, physiological porcine tissue, and pathological porcine tissue) was analyzed using the Pearson correlation coefficient.Results: All the HMSI cameras examined were able to provide the characteristic spectral properties of blood and tissues. A pushbroom camera and two snapshot systems achieve Pearson coefficients of at least 0.97 compared to the ground truth, indicating a very high positive correlation. Only one snapshot camera performs moderately to high positive correlation (0.59 to 0.85).Conclusion: The knowledge of the suitability of HMSI cameras for accurate measurement of chemical properties of biological objects offers a good opportunity for the selection of the optimal imaging tool for specific medical applications, such as organ transplantation.
Highlights
Four spectral cameras have been used in this study, which are based on two different acquisition techniques
Four spectral curves are achieved from the measurements: (1) spectrometer reference data (λ 1⁄4 400 to 1000 nm with step size 1∕3 nm), (2) hyperspectral pushbroom camera (λ 1⁄4 500 to 995 nm giving 100 bands in step size 5 nm), (3) multispectral 41-bands setup (λ 1⁄4 463 to 966 nm giving 41 bands), and (4) multispectral 3 × 3-VIS snapshot camera (λ 1⁄4 430 to 700 nm giving eight bands)
This study compares different spectral cameras for a possible clinical use, such as organs surveillance during transplantation by monitoring organ and blood specific spectral features
Summary
One of the largest problems for the transplantation medicine is the lack of donor grafts.[1]. 2017, the need for organs in 2019 (9271 organs required) far exceeds the number of available donor organs (3767 organs transplanted).[2]. This high demand for donor organs shows in particular the need to increase the number of successfully transplanted organs. A total of 2291 kidneys has been available for transplantation in 2018, compared to 7526 open transplant recipients at the end of the year.[3]. Apart from this shortage, the rejection rate for available kidney transplants has been 14.8% in 2019.2 Due to the lack of an accurate predictive organ evaluation strategy, certain organs were rejected they would still have been suitable for transplantation.[4–7]. In addition in the years 2014 to 2019, intra- or postoperative complications of kidney transplantations requiring a second kidney transplantation have been between 15.3% and 20.4%.2,3,8 an optical evaluation tool to monitor organ quality before transplantation would be of great interest
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
