Comparison of different methods for the preparation of porous bone substitution materials and structural investigations by synchrotron μ‐computer tomography

Abstract

AbstractThe preparation of porous biomaterials for bone substitution is an important clinical issue in current biomedical technology because the ingrowth of bone can only occur if a suitable number of sufficiently large pores is available. Different procedures are compared here: The combined chemical‐thermal treatment of bovine and human cancellous bone, the calcination of bovine cancellous bone, mechanical hole‐drilling, and the extraction of porogens (in this case: salt crystals). The inner structure and the porosity of all samples were studied using high‐resolution synchrotron μ‐computer tomography.