Abstract
Background and Aims : Familial Hypercholesterolemia (FH) is a monogenic, common autosomal disorder of lipid metabolism. Genetic diagnosis includes the study of 3 genes: LDLR, APOB, PCSK9, but 50-60% of clinical FH patients present a negative result. The present work aims determine if the cause of hypercholesterolemia in FH negative individuals can be explained by a polygenic contribution and compare three different LDL-C genetic risk score (GRS) in clinical FH patients.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
