Abstract
Background. Sentinel lymph node biopsy (SLNB) is the standard for axillary staging in breast cancer, Techniques for SLN include the use of radioisotope, blue dye, or a combination of both. Sentinel lymph node biopsy with 2 mL of superparamagnetic iron oxide (SPIO) tracer has shown to be non-inferior to the standard radioisotope technique in several studies. The aim of this study is to assess if the efficacy of SLN detection using Sentimag®/SiennaXP®, with different doses of the SPIO is non inferior to the conventional technique (radioisotope).
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