Abstract
Abstract Capillary zone electrophoresis (CZE) is an efficient microseparation technique that can be used for the separation of small as well as large biomolecules. The use of micelles in the buffer makes CZE an acceptable technique for the resolution of charged and neutral molecules. The separation of chiral compounds is an important aspect of the pharmaceutical industry, synthetic organic chemistry and other areas. Optical isomers can be separated from each other using high pressure liquid chromatography (HPLC) and capillary gas chromatography (CGC), however, each of these techniques has its limitations. CGC and HPLC require a chiral column, which is costly, CZE does not. CZE has the highest efficiency and chiral separations are achieved by adding a modifier to the buffer that facilitates the separation of optical isomers. In this review the advantages and disadvantages of HPLC, CGC and CZE for chiral separations will be discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
