Comparison of changes in salivary ph after chewing guava leaves (Psidium Guajava) and xylitol gum: A randomized, single-blind, crossover study

Abstract

Background: The medicinal benefits of guava have been discussed in many ethnopharmacological studies. Extract from the guava leaves is known for its spasmolytic, antioxidant, antimicrobial, anti-inflammatory, and antibacterial properties. Its effects on saliva have been least explored. The study aimed at evaluating the effect of chewing guava leaves and xylitol gum on salivary pH. Materials and Methods: The study design was a randomized, single-blind, crossover type. Forty-five volunteers were chosen based on selection criteria for the study. The participants were asked to chew guava leaf and sugar free xylitol chewing gum for about 90 s and the salivary pH was assessed. Results: There was no statistically significant difference in pH on comparing the two groups. pH comparisons between different time intervals showed significant differences in both groups (P = 0.001). Post hoc comparisons of pH after chewing guava leaves showed significant differences between different time intervals (P = 0.001) except between 30 and 60 min (P = 0.377). Post hoc comparisons in the xylitol group showed significant differences between different time intervals (P = 0.001) except between baseline and 30 min (P = 0.071) and between 30 and 60 min (P = 0.83). Conclusion: Chewing guava leaves showed a similar effect and had a better short-term effect when compared to xylitol chewing gum at different time intervals.