Abstract
The objective is to determine the usefulness of cathepsin L (Cat L) activity derived from the stratum corneum as an index of skin conditions by comparing the cheek and the forearm, in 20 female young adults. The sebum quantity, hydration index, melanin index and pH were measured with a sensor system consisting of a sebumeter, a corneometer, a mexameter and a pH meter. The stratum corneum was collected using tape stripping. Cat L and total protein (TP) were analyzed and the Cat L/TP ratio was calculated. Our results indicated that (i) chronic sun exposure causes an increase in Cat L activity; and (ii) in order to cancel out the influence of the collecting technique, it is very important to measure the Cat L/TP ratio. It is considered that the Cat L/TP ratio may be a useful index of the skin conditions in humans.
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