Abstract
Background The inflammatory mucosa of the sinus cavities is called sinusitis and is divided into various types based on its appearance and sign. Chronic rhinosinusitis is an inflammatory-infectious disease that involves the frontal, sphenoid, ethmoid, and maxillary sinuses. Chronic sinusitis is a multifactorial disease and the range of causes varies from environmental factors to genetic factors. The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. Methods In this descriptive-analytical study, the population under study included those with chronic sinusitis referred to Birjand Valiasr Hospital in 1397.3 cc of blood samples were taken 1 day before surgery to evaluate eosinophil counts and serum IgE levels. Also, samples taken from patients during surgery were counted, and then, 100 cells were counted, and eosinophil counts and percentages were calculated. The data were entered into the SPSS software after data collection. Results This study was performed on 70 patients with chronic rhinosinusitis which included 43 men (61.4%) and 27 women (38.6%) with mean age of 39.11 ± 13 13.72 years. There was no significant difference between sex of patients and mean serum IgE level (P < 0.05). The mean percentage of eosinophils in blood samples and tissues of patients with chronic sinusitis was significantly increased with the increase in CT scan (P < 0.05). Conclusions Tissue or blood eosinophilia was not observed in patients with chronic rhinosinusitis. Also, the mean eosinophil percentage of blood and tissue increased significantly in patients with increased scanning computed tomography (P < 0.05).
Highlights
Rhinosinusitis or sinusitis is an inflammation in the lining of the sinuses cavities
3 cc of blood samples was taken from patients to assess the number of eosinophils and serum IgE levels
Most of the patients examined in this study were housewives with a frequency of 23 patients (32.9%), and most of the patients lived in urban areas (80%) and were married (80%)
Summary
Rhinosinusitis or sinusitis is an inflammation in the lining of the sinuses cavities. Its symptoms include feeling of pressure and fullness in face, dryness, dry coughs, nasal congestion and obstruction, anterior and posterior nasal discharge, intermittent headaches, swelling and forehead or cheek erythema, olfactory dysfunction, edema, fatigue, and congestion of nasal mucosa [8,9,10] This disease imposes high financial burden on Iran’s health system. The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. The mean percentage of eosinophils in blood samples and tissues of patients with chronic sinusitis was significantly increased with the increase in CT scan (P < 0:05). The mean eosinophil percentage of blood and tissue increased significantly in patients with increased scanning computed tomography (P < 0:05)
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