Comparison of bioimpedance and oesophageal Doppler cardiac output monitoring during abdominal aortic surgery

Hk Jørgensen,T Gilsaa,J Bisgaard

doi:10.1186/cc10825

Abstract

Abdominal aortic surgery is a high-risk procedure. Cardiac output monitoring allowing haemodynamic optimisation may reduce the complication rate. Minimally invasive, continuous techniques are preferable. Cardiac output using oesophageal Doppler has been validated in several studies, showing good agreement with the gold standard. The aim of this study was to assess the degree of correlation and agreement between cardiac output measured by oesophageal Doppler and bioimpedance obtained from an endotracheal tube.

Highlights

Sepsis is primarily a disease of the aged and 60% of sepsis occurs in patients older than 65 years, 80% of deaths due to sepsis occur in this age group
The purpose of the study is to elucidate the immunological changes that occur in Klotho mice after sepsis in order to identify therapeutic targets for sepsis that occurs in aged individuals
We found significant associations between serum glial fibrillary acidic protein (GFAP) levels and mortality in pooled analysis of three studies (GMR 14.73; I2 = 79%), and between GFAP and Glasgow Outcome Scale (GOS) ≤3 in three studies (GMR 8.80; I2 = 77%)

Summary

Introduction

Sepsis is primarily a disease of the aged and 60% of sepsis occurs in patients older than 65 years, 80% of deaths due to sepsis occur in this age group. The aim was to evaluate the association between admission levels of CFD and severe sepsis outcome in patients hospitalized in intensive care utilizing the new assay. Implementation of a ventilator-associated pneumonia (VAP) bundle as a performance improvement project in the critical care units for all mechanically ventilated patients aiming to decrease the VAP rates over the study period at four major teaching hospitals in Damascus. The combination of high positive end-expiratory pressure (PEEP) and low tidal volume (VT) decreases some risks of mechanical ventilation, including pulmonary overdistention, damage due to cyclic opening and closing of the alveoli, and inflammatory responses that can lead to multiple-organ dysfunction. The timing and location for optimal post-ICU rehabilitation programs remain to be established

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