Comparison of biochemical/haematological parameters in healthy vs preeclamptic females

Abstract

Objectives: To evaluate and compare the Biochemical/Haematological parameters in healthy (pregnant subjects) vs preeclamptic females. Methodology: This descriptive cross-sectional study was planned/conducted at IBMS KMU Peshawar and the data was collected from the Dept. of Gynaecology & Obstetrics-Lady Reading Hospital Peshawar, from June 2019 to July 2020. One hundred thirty-eight pregnant subjects between the gestational ages of 26-30 weeks were included in the study. The subjects were divided into two cohorts; Patients with preeclampsia (Group I N=92) and a Normotensive Control Group; women with normal pregnancy (Control group N=46). Blood from the subjects was checked for Haemoglobin (Hb) and Platelet (PLT) levels and Body Mass Index (BMI) among other parameters. Blood was taken and analysed at the Hospital Lab via Cobas 6000 analyser. Data was analysed using SPSS version 26.0 for MacBook Pro. Results: Body mass index of PE group was significantly higher compared to normal group (p<0.001). Similarly, mean platelet counts and hemoglobin in PE group was lower as compared to normo-tensive group and the differences were statistically significant (p<0.05). There was no significant difference in mean gestational age (weeks) between the two groups (27.83 ± 0.95 vs 27.78 ± 1.07, p= 0.33) was observed.