Abstract

A comparative analysis of the post-drive recovery patterns of the sinus node following equal numbers of sinus captures from right atrial and right ventricular drive was investigated in 15 dogs. Despite similar numbers of sinus captures, the post-drive recovery pattern was significantly different for atrial and ventricular drive. Sinus acceleration after ventricular drive contrasted with suppression after atrial drive and increased to a maximum by the third to fifth beat after drive. Differences in recovery patterns were less evident after extrinsic cardiac denervation. Arterial and atrial pressure changes resulting from differences in the atrioventricular contraction sequence during atrial and ventricular drive suggest a possible basis for these findings.

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