Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit

Abstract

Acute Physiology and Chronic Health Evaluation II (APACHE II) and Modified Charlson Index (MCI) are used to predict the fatality in intensive care units (ICU). We aimed to investigate the difference between these scores in the prediction of fatality in the medical intensive care unit. Our study is important because in our literature overview, this study is one of the rare studies that compares these scoring systems. 108 ICU patients included. In all subjects APACHE II and MCI performed. Procalcitonin, C-reactive protein(CRP) levels of patients were recorded. Patients were then grouped according to mechanically ventilated or not; mortality happened or not. Statistically significance found in age(p<0.045), mechanical ventilation, procalcitonin, CRP and MCI (p<0.001) about mortality . MCI sensitivity and specifity were higher than APACHE II in %95 confidance interval. Area under curve in ROC analysis was CRP (0.728), Procalcitonin (0.719), MCI (0.686), APACHE II (0.665) respectively. Our study demonstrates that the Modified Charlson Index combined with procalcitonin and CRP can be used for predicting mortality in medical ICU as well as APACHE II