Abstract
Currently, there is a constant search for new chemical compounds through plant extracts and phytochemical compounds that do not cause so many side effects in the oral cavity and that have good antimicrobial properties. Therefore, the present study evaluated the synergistic antimicrobial efficacy of mouthwashes containing thymol and carvacrol when compared with 0.12% chlorhexidine mouthwash after bilateral lower third molar extraction. Nineteen healthy (male and female) patients (n = 19) aged between 18 and 30 years, of both sexes, treated at the Faculty of Dentistry of Mato Grosso do Sul (UFMS, MS, Brazil) participated in this study. All patients were submitted to two different therapeutic treatments, divided into two groups: group 1 (control) - patient used 0.12% chlorhexidine mouthwash solution; group 2 (experimental) - patient used 0.05% thymol and 0.025% carvacrol solutions. The suture was removed at seven postoperative days and aseptically transferred to a tube containing sterile potassium buffer saline solution. Samples were submitted to microbiological analysis at the Microbiology Laboratory at UFMS. The mean and standard deviation of colony forming units/ml of isolate microorganisms in the suture grown in BHI agar obtained from the control and experimental groups were 4.766 x 106 ± 4.069 and 4.847 x 106 ± 3.971, respectively. In conclusion, the thymol and carvacrol based mouthwash showed antimicrobial effectivity in biofilm adherence of the silk thread after extraction of third molars.
Highlights
Third molar extraction is one of the most common surgical procedures in dental clinics
Suture threads made of silk, cotton and nylon are most commonly used in intra-oral surgery (Santos & Machado, 2001)
Silk and cotton threads are widely used in oral surgery because they are easy to use, the knots do not untie, for their low tensile strength, low cost and their ends do not cause injury and ulceration in the buccal mucosa (Qin et al, 2010)
Summary
Third molar extraction is one of the most common surgical procedures in dental clinics. It is extremely important to reposition the displaced soft tissue by using sutures. This procedure helps wound healing by maintaining the flap in place; by coapting the edges of the surgical wounds, stimulating healing by first intention. Suture threads made of silk, cotton and nylon are most commonly used in intra-oral surgery (Santos & Machado, 2001). Silk and cotton threads are widely used in oral surgery because they are easy to use, the knots do not untie (low memory), for their low tensile strength, low cost and their ends do not cause injury and ulceration in the buccal mucosa (Qin et al, 2010)
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