Comparison of Antibacterial Efficacy of Silver Particle Added Portland Cement and Mineral Trioxide Aggregate

Abstract

Statement of the problem: Despite the studies on the antibacterial effect of mineral trioxide aggregate (MTA), there are few studies comparing the anti-bacterial activity of MTA with silver nanoparticle added Portland Cement (PC). Objective: The study aimed to compare the antibacterial activity of MTA with silver nanoparticle added PC. Materials & Methods: MTA, mixed with distilled water, poured into silicone molds containing disc-shaped spaces with a diameter of 5 mm and a height of 2 mm (n = 7). Silver nanoparticles of 100 nm size were added to PC at a concentration of 1% by volume, and 7 disc samples were prepared by mixing with distilled water (PAG-DW group). Finally, PC containing 100 nm silver par-ticles at 1% concentration was mixed with 0.12% chlorhexidine gluconate (CHG) and seven specimens of PAG-CHG were obtained by pouring this mixture into the same silicone molds. Then, all samples in these three groups were placed in the diffusion agar test (DAT) created with six different microor-ganisms. Inhibition zone diameters formed by the discs were measured to de-termine the antibacterial activity. Results: The samples of PAG-DW and PAG-CHG formed statistically significantly larger inhibition zones in DAT when compared to samples of MTA (P=0.001). Conclusion: The antimicrobial activity of PC with added silver nano-particles was significantly higher than that of MTA. Mixing PC with CHG also increased its the antibacterial activity.