Abstract
PurposeTo compare the anterior chamber depth (ACD), keratometry (K) and astigmatism measurements taken by IOLMaster and Pentacam HR in normal and high myopic (HM) eyes.DesignA prospective observational case series.MethodsSixty-six normal eyes and 59 HM eyes underwent ACD, keratometry and astigmatism measurements with both devices. Axial length (AL) was measured on IOLMaster. The interdevice agreement was evaluated using the Bland-Altman analysis and paired t-test. The correlations between age and AL & ACD were analyzed. Vector analysis was used to compare astigmatism measurements.ResultsThe ACD from IOLMaster and Pentacam HR was different for the normal group (P = 0.003) but not for the HM group (P = 0.280). IOLMaster demonstrated higher steep K and mean K values than Pentacam HR for both normal and HM groups (P<0.001 for all). IOLMaster also have higher flat K values for the HM groups (P<0.001) but were statistically equivalent with Pentacam HR for the normal group (P = 0.119) IOLMaster and Pentacam HR were different in astigmatism measurements for the normal group but were statistically equivalent for the HM group. For the normal group, age was negatively correlated with AL, IOLMaster ACD and Pentacam HR ACD (r = -0.395, P = 0.001; r = -0.715, P < 0.001; r = -0.643, P < 0.001). For the HM group, age was positively correlated with AL but negatively correlated with IOLMaster ACD and Pentacam HR ACD (r = 0.377, P = 0.003; r = -0.392, P = 0.002; r = -0.616, P < 0.001).ConclusionsThe IOLMaster and Pentacam HR have significant difference in corneal power measurements for both normal and HM groups. The two instruments also differ in ACD and astigmatism measurement for the normal group. Therefore, a single instrument is recommended for studying longitudinal changes in anterior segment biometric measurements. Age should be considered as an influencing factor for both AL and ACD values in the normal and HM group.
Highlights
The anterior chamber depth (ACD) from IOLMaster and Pentacam HR was different for the normal group (P = 0.003) but not for the high myopia (HM) group (P = 0.280)
IOLMaster have higher flat K values for the HM groups (P
For the HM group, age was positively correlated with axial length (AL) but negatively correlated with IOLMaster ACD and Pentacam HR ACD (r = 0.377, P = 0.003; r = -0.392, P = 0.002; r = -0.616, P < 0.001; Fig 3)
Summary
Accurate anterior chamber depth (ACD) and anterior corneal power measurements are important for the design and ultimate success of vision correction, including refractive and cataract surgery, especially for high myopia (HM).[1,2,3] Currently, a number of instruments are available to measure anterior segment biometry, including Scheimpflug topography, optical coherence tomography, optical low-coherence reflectometry, partial coherence interferometry and slit-scanning topography/pachymetry systems.[4,5,6,7]The Pentacam (OCULUS, Wetzlar, Germany), which uses a single rotating Scheimpflug camera (180°) and monochromatic slit-light source (blue LED at 470 nm) combined with a static camera, can provide a 3-dimensional model of the anterior segment. The ACD and anterior corneal keratometry measurements generated by the Pentacam have been shown to have excellent repeatability.[8] There is a special 3D high-resolution (HR) scanning mode, in which the camera takes 50 images in 1 second and 138,000 true elevation points are evaluated. This mode was claimed to provide better image quality with optimized optics and new software features like contact lens fitting and 3D pIOL simulation. The HR mode was used (referred to as Pentacam HR)
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