Comparison of amylase, lipase and d-dimer levels in the etiopathogenesis of mortality in Covid 19 pneumonia

Abstract

Objective: Coronavirus Disease 2019 (Covid-19) is a pandemic cause affecting the whole world with high mortality. The effects of lipase, amylase and d-dimer levels on mortality were investigated in Covid-19 pneumonia in the present study. Method: A total of 131 patients diagnosed with pneumonia due to Covid-19 and 60 healthy control groups were included in the study prospectively. The cases were divided into 3 groups as the healthy control group, those who recovered, and those who died. Those who had pneumonia in the lung tomography among the cases diagnosed with Covid-19 were examined. The RT-PCR (Real-Time Polymerized Chain Reaction) test results were recorded from the system. The serum lipase, amylase, albumin levels, WBC (White Blood Cell), N/L (Neutrophil/Lymphocyte Ratio), and CRP (C-Reactive Protein) levels of the patients were compared with those of the Control Group. Results: When all the data were reviewed, the Lipase, Amylase, and d-dimer levels were found to be statistically significantly higher in the exitus group when compared to the control group, and T. protein and albumin levels were lower (p<0.01). Other acute phase reactants, WBC, N/L Ratio, and CRP levels were significantly higher (p<0.01). As a result of the comparison of the recovered and exitus group, no statistically significant changes were detected in all parameters (p>0.05). Conclusions: The elevation in serum amylase, lipase, and d-dimer levels may be significant in prognosis in pneumonia developing due to Covid-19.