Abstract
Purpose The purpose of this study was to evaluate the relationship between ambulatory, and central blood pressure (BP) in heart transplant recipients. Methods We conducted a cross-sectional study in 97 adult heart transplant recipients. Twenty-four hour ambulatory BP was measured using a Takeda TM-2430 instrument (A&D Medical, Tokyo, Japan) with readings taken every 30 minutes. Central hemodynamics were evaluated in the sitting position after 10 min of rest using the SphygmoCor system (AtCor Medical, Sydney, Australia). We compared ambulatory BP measurements with central BP readings. Results The mean age of the studied subjects was 50 ± 15 years, and 68.0% of participants were male. Bland-Altman analysis showed a bias (mean of difference) of 17.4 ± 18.8 mmHg for 24-hour systolic BP, 17.9 ± 17.9 mmHg for daytime systolic BP, and 16.1 ± 21.7 mmHg for nighttime systolic BP compared with central systolic BP. The strongest correlation was observed between daytime systolic BP and central systolic BP (r=0.344, p Conclusion Daytime systolic BP was higher on average than central systolic BP, but the higher range of daytime systolic BP exhibited larger difference with central systolic BP. Long-term studies are needed to determine which of the central BP or ambulatory BP better predicts the prognosis of heart transplant recipients.
Published Version
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