Comparison of Ajust sling vs. tension-free vaginal tape-obturator sling in the treatment of female stress urinary incontinence

Abstract

Objective To compare the efficacy and safety of Ajust sling vs. tension-free vaginal tape-obturator (TVT-O) sling in the treatment of female stress urinary incontinence (SUI). Methods Eighty female patients with SUI of initial treatment were randomized by envelope technique to either Ajust sling or TVT-O sling, and the baseline data, perioperative index, complications and treatment effect were compared between the two groups. Results The operation time was shorter, intraoperative blood loss was less, and postoperative visual analogue scale (VAS) score was better in the Ajust group [(14.7±3.9) min, (14.5±5.7) ml, (2.7±0.8) score] than those in the TVT-O group [(21.8±7.3) min, (20.4±7.9) ml, and (3.8±1.1) score; t=5.426, P=0.000; t=3.830, P=0.000; t=5.115, P=0.000]. The groin pain (2 cases) and the overall complication (5 cases) in the Ajust group were significantly decreased as compared with those in the TVT-O group (10 and 21 cases; χ2=6.275, P=0.012; χ2=14.587, P=0.000). The objective cure rate and the subjective cure rate in the Ajust group were 95.0% and 95.0%, and those were 95.0% and 92.5% in the TVT-O group (P=1.000, P=0.000). The postoperative ICIQ-SF score, I-QOL score, FSFI score in the Ajust group [(1.6±0.9), (95.8±5.6), (29.5±7.9) score] and those in the TVT-O group [(1.5±1.1), (96.5±4.4), (30.3±7.1) score] were significant different from those preoperation [(13.2±2.9), (55.7±10.3), (22.4±6.8) score in the Ajust group; (13.8±2.4), (57.0±7.7), (21.9±7.2) score in the TVT-O group; the Ajuest group: t=24.161, P=0.000; t=21.632, P=0.000; t=4.308, P=0.000; the TVT-O group: t=29.466, P=0.000; t=28.169, P=0.000; t=5.254, P=0.000], but there was no statistically significant difference between the two groups (t=0.445, P=0.658; t=0.622, P=0.536; t=0.476, P=0.635). Conclusion As compared with TVT-O sling, Ajust sling is safe and effect in the treatment of female SUI with less complications. Key words: Stress urinary incontinence; Adjustable single incision mini sling; Tension-free vaginal tape-obturator