Comparison of age related pregnancy rates (PR) in women using different ovulation induction (OI) methods

Abstract

ObjectiveTo determine if a specific OI method is beneficial for the treatment of infertility in patients of a particular age group.DesignA retrospective analysis of 4448 OI cycles with intrauterine inseminations (IUIs) in women undergoing treatment for infertility.Materials and methodsWomen undergoing IUI cycles using different OI methods from January 2001 to December 2003 were analyzed for clinical PR. Clinical pregnancy was defined as the presence of an intrauterine sac documented by ultrasound. Patients were grouped according to ovulation inductionMethodNatural, Clomiphene citrate (CC) 25, CC50, CC100, CC150, >CC150, and FSH. In each of these groups, the patients were further divided according to age: < 30, 30–34, 35–39, 40–42, and > 42. Age related PR differences between OI groups were determined statistically by Chi Square analysis.ResultsSignificant differences in PR were seen for women 30–39 amongst the different OI methods as shown in Tables 1 and 2. p values are as follows: ap<0.05 vs. Natural; bp<0.05 vs. Total CC p values are as follows: ap<0.05 vs CC50; bp<0.05 vs. CC150ConclusionView Large Image Figure ViewerDownload Hi-res image Download (PPT) ObjectiveTo determine if a specific OI method is beneficial for the treatment of infertility in patients of a particular age group. To determine if a specific OI method is beneficial for the treatment of infertility in patients of a particular age group. DesignA retrospective analysis of 4448 OI cycles with intrauterine inseminations (IUIs) in women undergoing treatment for infertility. A retrospective analysis of 4448 OI cycles with intrauterine inseminations (IUIs) in women undergoing treatment for infertility. Materials and methodsWomen undergoing IUI cycles using different OI methods from January 2001 to December 2003 were analyzed for clinical PR. Clinical pregnancy was defined as the presence of an intrauterine sac documented by ultrasound. Patients were grouped according to ovulation induction Women undergoing IUI cycles using different OI methods from January 2001 to December 2003 were analyzed for clinical PR. Clinical pregnancy was defined as the presence of an intrauterine sac documented by ultrasound. Patients were grouped according to ovulation induction MethodNatural, Clomiphene citrate (CC) 25, CC50, CC100, CC150, >CC150, and FSH. In each of these groups, the patients were further divided according to age: < 30, 30–34, 35–39, 40–42, and > 42. Age related PR differences between OI groups were determined statistically by Chi Square analysis. Natural, Clomiphene citrate (CC) 25, CC50, CC100, CC150, >CC150, and FSH. In each of these groups, the patients were further divided according to age: < 30, 30–34, 35–39, 40–42, and > 42. Age related PR differences between OI groups were determined statistically by Chi Square analysis. ResultsSignificant differences in PR were seen for women 30–39 amongst the different OI methods as shown in Tables 1 and 2. p values are as follows: ap<0.05 vs. Natural; bp<0.05 vs. Total CC p values are as follows: ap<0.05 vs CC50; bp<0.05 vs. CC150 Significant differences in PR were seen for women 30–39 amongst the different OI methods as shown in Tables 1 and 2. p values are as follows: ap<0.05 vs. Natural; bp<0.05 vs. Total CC p values are as follows: ap<0.05 vs CC50; bp<0.05 vs. CC150 Conclusion