Comparison of Abdominal Visceral Adipose Tissue Area Measured by Computed Tomography with That Estimated by Bioelectrical Impedance Analysis Method in Korean Subjects.

Dong-Hwa Lee,Kyong Jung,Jae Moon,Kyong Park,Eu Ku,Kyeong Park,Kyoung Kim,Sung Choi,Soo Lim,Soyeon Ahn,Hak Jang,Yoon Kim

doi:10.3390/nu7125548

Abstract

We evaluated the concordance between visceral fat area (VFA) estimated by bioelectrical impedance analysis (BIA) or computed tomography (CT) in Korean subjects with a wide range in age and body mass index (BMI). In 1006 individuals (mean age 55.2 ± 11.8 (19–87) years, mean BMI 26.0 ± 3.5 (17–46) kg/m2, 48.9% men), VFA quantified by CT was compared with VFA using multifrequency BIA machines within 15 days. Concordance rates were compared by age or BMI using correlation analysis, Bland-Altman plots, and intraclass correlation coefficient (ICC). Using BIA data, we established a regression formula to reflect CT-VFA. The mean VFAs by CT and BIA were 131.9 ± 57.3 cm2 and 110.5 ± 33.9 cm2, respectively (r = 0.605, p < 0.001). The mean difference was 21.4 ± 45.6 cm2, tending to increase with BMI. In women with BMI <25 kg/m2 or age <50 years, the VFAs by BIA were similar to those by CT (ICC = 0.496 in BMI <25 kg/m2 and ICC = 0.638 in age <50 years). However, the difference was greater in men with BMI ≥25 kg/m2 or age ≥50 years. Applying our formula, the difference between estimations decreased to 0.2 ± 38.2cm2. VFA estimated by BIA correlated well with that by CT, but a more accurate formula is needed to match CT data, particularly in older men or subjects with a high BMI.

Highlights

The prevalence of obesity has increased dramatically over the last several decades worldwide and is a major public health problem [1]
We investigated the concordance rates between visceral fat area (VFA) estimated by bioelectrical impedance analysis (BIA) and that measured by computed tomography (CT) in a large number of people with wide ranges in age and body mass index (BMI) values
Abdominal VFAs estimated by BIA were significantly correlated with those Imnetahsiusrsetdudby, aCbTdo(rm=in0a.6l0V5F, Ap s

Summary

Introduction

The prevalence of obesity has increased dramatically over the last several decades worldwide and is a major public health problem [1]. A large amount of visceral adipose tissue is a core component in subjects with metabolic syndrome [6,7]. In this context, accurate measurement of the visceral fat area (VFA) is critical in the assessment of cardiometabolic risk for each individual. Technical and ethical issues have been increasing regarding the use of CT for large-scale studies. Because of these limitations, various alternative methods have been tried to assess VFA [9,10,11]. US has the limitation of inter- and intra-examiner variation

Methods

Discussion

Conclusion