Abstract

In Korea, lung cancer is a common cancer, and has the highest mortality rate in both males and females. Approximately 80% of lung cancer is due to smoking, and the remaining cases are known to be due to genetic factors, history of respiratory disease, infection, diet, and occupational and environmental factors. Since the occupational and environmental hazards may differ from region to region, the lung cancer risk may differ too. To identify this, we selected seven metropolitan cities, and compared occupational and environmental hazards. Furthermore, we calculated smoking rate adjusted standardized rate ratio (ratio of 10-year cumulative age-standardized incidence rate of lung cancer during the 2000–2009 period at target region versus reference region) to compare the regional lung cancer risk. The result showed that the emissions and concentrations of air pollutant were higher in high-risk regions, and the risk of lung cancer was significantly elevated in such area. In this study, we simultaneously consider the cumulative incidence, age-standardization and smoking rate adjustment. Therefore, we can conclude that the validity of the finding of this study is higher than that of past studies. In conclusion, the occupational and environmental hazards have an effect on lung cancer.

Highlights

  • In Korea, the Ministry of Health and Welfare started a cancer registry in 1980; they publish annual reports of cancer statistics, including the country’s cancer incidence data and the status of cancer occurrence throughout Korea

  • More than 190 hospitals participate in the Korea Central Cancer Registry (KCCR), and the database covers more than 90% of the new cancer cases in Korea

  • In order to compare the risk of lung cancer among target regions, we calculated Standardized rate ratio (SRR) which is the ratio of the age-standardized incidence rate (ASR) in this study

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Summary

Introduction

In Korea, the Ministry of Health and Welfare started a cancer registry in 1980; they publish annual reports of cancer statistics, including the country’s cancer incidence data and the status of cancer occurrence throughout Korea. According to the annual report of 2015, lung cancer is the second most common malignant neoplasm in males, and the fifth most common in females [1] Res. Public Health 2018, 15, 1259; doi:10.3390/ijerph15061259 www.mdpi.com/journal/ijerph

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