Comparison of 60-minute vs 30-minute transcranial direct current stimulation (tDCS) in major depressive disorder: Effects on depression suicidal ideation and anxiety

Ni Zhou,Weichieh Yang,Shentse Chen,Chunbo Li,Wu Hong,Yiru Fang,John M Davis ,Haijing Huang,Nuoshi Qian,Zheyi Wei,Dongbin Lyu,Robert C Smith ,Shuxiang Shi,Mengke Zhang,Yiming Chen,Shuqi Kong,Qinte Huang,Hua Jin,Fan Wang,Chenglin Wu

doi:10.1016/j.psychres.2023.115556

Comparison of 60-minute vs 30-minute transcranial direct current stimulation (tDCS) in major depressive disorder: Effects on depression suicidal ideation and anxiety

Ni Zhou, Weichieh Yang + Show 18 more

Open Access

https://doi.org/10.1016/j.psychres.2023.115556

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Journal: Psychiatry Research	Publication Date: Nov 2, 2023
Citations: 1	License type: cc-by

Affiliation: Shanghai University, Shanghai Mental Health Center, Shanghai Jiao Tong University, Center for Excellence in Brain Science and Intelligence Technology, Institute of Psychology, Chinese Academy of Sciences, Ruijin Hospital, Johns Hopkins University, Johns Hopkins Medicine, University of Illinois at Chicago, Shenzhen Institutes of Advanced Technology, Shanghai Changning Mental Health Center, Nathan Kline Institute for Psychiatric Research, New York University, University of California, San Diego, VA San Diego Healthcare System, Tongji University

#Depression Suicidal Ideation #ITT Analysis + Show 8 more

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Abstract

We investigated whether changes through doubling the duration of each tDCS session would increase efficacy of tDCS for depression. tDCS was applied for 10 sessions, followed by two additional weekly sessions. 63 patients with MDD underwent randomization, with 22 being assigned to 60-min/d group, 25 to 30 min/d group, and 16 to sham group. HAMD-17 reductive ratios at week 2 and 4 were of no significant differences among treatment groups. 60 min group had a greater decrease in anxiety compared to 30 min group and sham group based on HAMA at 4 weeks but only in the completer analysis, not in ITT analysis.

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