Abstract
Inhaled anaesthetics are the widely used drugs for the induction and maintenance of general anaesthesia. The evolution of volatile anaesthetics began with the introduction of Diethyl ether46, Nitrous oxide to the modern inhaled anaesthetics like Desurane and Sevourane(1). These modern inhaled anaesthetics form the important tool for altering the central nervous system functions in patient undergoing general anaesthesia. In 1950, all halogenated anaesthetics with an exception of Nitrous oxide were ammable and potentially toxic to the liver. Replacing the hydrogen atom with a uorine atom led to introduction of newer anaesthetics which are non-inammable and are resistant to metabolism(2).
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