Abstract

Vertebra metastases can be seen during the prognosis of cancer patients. Treatment ways of the metastasis are radiotherapy, chemotherapy and surgery. Three-dimensional conformal therapy (3D-CRT) is widely used in the treatment of vertebra metastases. Also, Intensity Modulated Radiotherapy (IMRT) and Volumetric Arc Therapy (VMAT) are used too. The aim of this study is to examine the advantages and disadvantages of the different radiotherapy techniques. In the aspect of this goal, it is studied with a randophantom in Uludag University Medicine Faculty, Radiation Oncology Department. By using a computerized tomography image of the phantom, one 3DCRT plan, two VMAT and three IMRT plans for servical vertebra and three different 3DCRT plans, two VMAT and two IMRT plans for lomber vertebra are calculated. To calculate 3DCRT plans, CMS XiO Treatment System is used and to calculate VMAT and IMRT plans Monaco Treatment Planning System is used in the department. The study concludes with the dosimetric comparison of the treatment plans in the spect of critical organ doses, homogeneity and conformity index. As a result of this study, all critical organ doses are suitable for QUANTEC Dose Limit Report and critical organ doses depend on the techniques which used in radiotherapy. According to homogeneity and conformity indices, VMAT and IMRT plans are better than one in 3DCRT plans in servical and lomber vertebra radiotherapy plans.

Highlights

  • Treatment rate is increasing for elderly patients at 65 and more ages with the increasing population age today

  • The homogeneity index value is found to be the best in treatment planning calculated by Volumetric Arc Therapy (VMAT) and Intensity Modulated Radiotherapy (IMRT) techniques

  • The optimal conformity index value in cervical vertebra treatment planning was obtained by treatment plans calculated by VMAT and IMRT techniques

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Summary

Introduction

Treatment rate is increasing for elderly patients at 65 and more ages with the increasing population age today. The treatment of patients with vertebral metastases is decided by considering several factors These factors are; clinical data, duration of present symptoms, tumour type, radiosensitivity, tumour location, non-vertebral extension, vertebra length and medical status of the patient [4]. Techniques such as Intensity Modulated Radiotherapy (IMRT) and Volumetric Arc Therapy (VMAT) are used in the radiotherapy of vertebral metastases, as well as conventional planning techniques. The IMRT and VMAT methods allow the dose to accumulate in tumour volume, preserving normal tissues This feature is very important for the patient in terms of the coming time. The aim of this study is to answer the question of which treatment planning method is best suited to the application of radiotherapy and the most appropriate for critical organs in patients with vertebral metastases from 3DCRT, IMRT and VMAT treatment methods

Treatment approaches to metastatic vertebras
Randophantom
Conformity and Homogeneity Indexes
Techniques
Conclusions
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