Comparison of β-tricalcium phosphate and autogenous bone graft with bioabsorbable membrane and autogenous bone graft in the treatment of intrabony periodontal defects: A clinico-radiographic study

Abstract

Aim: The aim of this study was to compare clinically and radiographically, the regenerative potential of β- tricalcium phosphate and autogenous bone graft with a bioabsorbable membrane and autogenous bone graft in the treatment of intrabony periodontal defects. Materials and Methods: A total of 24 sites from 12 patients showing bilateral or contralateral intrabony defects were selected and randomly divided into experimental site A (CERASORB® + autogenous bone graft) and experimental site B (BIOMEND™ + autogenous bone graft) by using the split mouth design. Clinical parameters like plaque index, was recorded at 1, 3, 6, 12 months and probing pocket depth (PPD), clinical attachment level (CAL) and gingival recession were recorded at baseline, 6 and 12 months along with radiographs to evaluate defect fill, change in alveolar crest height and percentage of defect fill. Statistical Analysis: For intragroup variations-Student paired t-test, for comparison between the two groups-unpaired t-test and for the comparison of plaque index at different time intervals-Wilcoxon matched pairs test were used. Results: Both groups showed clinically and statistically significant reduction in PPD and gain in CAL with no statistical significance. Radiographically, in site A there was significant defect fill of 69.58% and 79.24% at 6 and 12 months. In site B, a defect fill of 71.29% and 82.77% was seen at 6 and 12 months. Conclusion: Both groups showed the potential of enhancing the periodontal regeneration; however, on comparison between the two groups, the results obtained of the BIOMEND™ + autogenous bone graft group were slightly better, although statistically not significant.