Abstract
Background: To compare four different optical coherence tomography (OCT) devices for visualization of retinal and subretinal layers in highly myopic eyes. Methods: In this prospective, observational, cross-sectional study, consecutive patients with high myopia and control subjects were imaged by four OCT devices: Spectralis OCT2, PlexElite 2.0 100 kHz, PlexElite 2.0 200 kHz and the Canon Xephilio OCT-S1. The acquisition protocol for comparison consisted of single vertical and horizontal line scans centered on the fovea. Comparison between the devices in the extent of visible retina, presence of conjugate image or mirror artifacts, visibility of the sclerochoroidal interface and retrobulbar tissue. Results: 30 eyes with high myopia and 30 control subjects were analyzed. The visualized RPE length was significantly different between the OCT devices with Xephilio OCT-S1 imaging the largest extent (p < 0.0001). The proportion of eyes with conjugate image artifact was significantly higher with the Spectralis OCT (p < 0.0001), and lower with the PlexElite 200 kHz (p < 0.0001). No difference in visibility of the sclerochoroidal interface was noted among instruments. The retrobulbar tissue was visible in a higher proportion of eyes using swept-source PlexElite 100 kHz and 200 kHz (p < 0.007) compared to the other devices. Conclusions: In highly myopic eyes, the four OCT devices demonstrated significant differences in the extent of the retina imaged, in the prevalence of conjugate image artifact, and in the visualization of the retrobulbar tissue.
Highlights
Myopia is one of the most common eye problems, and is growing, affecting 1.6 billion individuals worldwide [1]
Advances in imaging technologies such as optical coherence tomography (OCT) and three-dimensional magnetic resonance imaging (MRI) have enhanced our understanding of the ocular changes associated with high myopia [3,6]
The retinal pigment epithelium (RPE) measurement was significantly different among the four instruments, which was most clearly evident in the Bland-Altman analysis (Figures 3 and 4)
Summary
Myopia is one of the most common eye problems, and is growing, affecting 1.6 billion individuals worldwide [1]. The retinal periphery and the posterior pole of high myopic eyes are prone to several complications that require careful assessment and monitoring [7,8]. Subsequent spectral-domain OCT technology allowed for a more detailed visualization of the posterior pole anatomy and enhanced view of deeper tissues [11,12]. The steep curvature of highly myopic eyes can impact the visualization of the posterior segment on OCT. Given the unique topographical challenges posed by these eyes and the increasing prevalence of myopia, evaluating the performance of current OCT devices would appear to be of importance. In this study we compared the visibility of retinal and subretinal structures in highly myopic eyes and normal emmetropic eyes using four different OCT devices
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
