Abstract
Hydrogenolysis of carbobenzoxy phenylalanine was carried out in the gas–liquid–liquid–solid four-phase upflow and trickle-bed reactor, and the performance of upflow and trickle-bed reactor was compared. The upflow reactor showed higher performance than the trickle-bed reactor. The apparent reaction order was zero to carbobenzoxy phenylalanine. Holdup of each phase was measured at various conditions to determine the reaction rate constant. From Arrhenius plot, the apparent activation energy in upflow reactor was 38.1 kJ/mol.
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