Abstract
Background: Multiple Sclerosis is a demyelinating disease which involve almost 2.5 million people all around the world. There are different MR pulse sequences which are used to detect MS plaques. This study is intended to compare, T2 weighted, STIR and PSIR pulse sequences, for the detection of cervical spinal cord lesions of patients with MS. Materials and Methods: 60 patients who definitely diagnosed as MS, participated in this study during 6 months from June to December 2016. 1.5 T Siemens (Avanto, Erlangen, Germany) MR scanner and three pulse sequences (T2 weighted, STIR and PSIR sequences) were used for cervical cord MR imaging in the patients. In order to assess the effectiveness of these pulse sequences, the lesion to cord ratio (LCR) and lesion to noise ratio (LNR) were calculated. Results: The LCR and LNR of the T2 and PSIR were the same, just the intensities were reverse. STIR had a significantly different LCR and LNR so it was better for the diagnosis of cervical cord MS plaques. Discussion and Conclusion: According to that results by using 1.5 Tesla MRI machine, it can imply that the STIR pulse sequence was the best pulse sequence in comparison to T2 and PSIR for detection of cervical cord MS plaques.
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