Comparison Between Score for Neonatal Acute Physiology Perinatal Extension II and Clinical Risk Index for Babies in Prediction of Neonatal Mortality in Septic Preterm Cases Tanta University Hospital’s Neonatal Intensive Care Unit

Abstract

Background: Preterm birth (< 37 weeks gestation) is a major cause of death and a significant cause of long-term loss of human potential amongst survivors all around the world.
 Aim: Compare between two neonatal mortality risk scores, Score for neonatal acute physiology perinatal extension (SNAP-PE II) and Clinical risk index for babies (CRIB), in predicting the neonatal mortality in septic preterm admitted to neonatal intensive care unit (NICU) of Tanta University Hospital (TUH) over a period of one year.
 Patients and Methods: This was a prospective cohort study carried out on 200 septic preterm newborns admitted to NICU of TUH over 1 year period. 89 cases representing (44.5 %) were female and 111 cases representing (55.5%) were male. All of them were admitted to NICU [within their first 48 hours of birth]. All septic preterm neonates will be followed up till their death or discharge. SNAP-PE II and CRIB scores applied to all the septic preterm neonates in this study during the first 12 hours after diagnosis of sepsis in NICU according to Modified Hematological scoring system (MHSS).
 Results: There was a weak positive correlation between MHSS score for neonatal infection and both of the SNAP II and CRIB scores.
 Conclusion: Both SNAP-PE II and CRIB scores have good sensitivity for predicting neonatal mortality which was slightly higher in SNAPPE II score. Neonatal Mortality rate was significantly correlated with high MHSS.