Comparison between rapid intravenous drip of Shenfu and pumping of Dopamine in interventional therapy of acute inferior wall myocardial infarction

Abstract

Objective To compare the effect of pressurized rapid intravenous drip of Shenfu and micro-pumping of dopamine on hypoperfusion in percutaneous coronary intervention (PCI) of acute inferior wall myocardial infarction. Methods A total of 80 patients with acute inferior wall myocardial infarction treated with emergency PCI in Chest Pain Unit of Yantaishan Hospital of Yantai City from May 2014 to May 2015 were enrolled. Then these patients were divided into observation group (n=40, pressurized rapid intravenous drip of normal saline and Shenfu) and control group (n=40, pressurized intravenous drip of normal saline with the same pressure combined with micro-pumping of Dopamine) according to random number table. Blood pressure and heart rate per five minutes were observed and recorded before intravenous drug, five to forty minutes after intravenous drug. Besides, the incidence rates of malignant arrhythmia, vomitting, TIMI grade three flows after intrqvenous drug and major adverse cardiovascular events after 30 days of a follow-up were also observed and recorded. Results Systolic pressure, diastolic pressure and mean arterial pressure of patients between two groups all met and maintained to the expectation after treatment with significant differences between two groups (P 0.05) . Conclusions When the hypoperfusion appears during PCI of acute inferior wall myocardial infarction, the pressurized rapid intravenous drip of Shenfu can improve hypoperfusion which is better than Dopamine in the effects of correcting hypotension and reducing the occurrence of adverse events. Key words: Dopamine; Shenfu injection; Myocardial infarction; Hypoperfusion; Percutaneous coronary intervention