Abstract
Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats.
Highlights
Since the use of titanium emerged in the manufacture of medical, dental implants, and osseointegration principles, several modifications to this material have appeared [1,2,3,4,5].These modifications aimed to increase the mechanical resistance and corrosion as well as improve the Materials 2020, 13, 1604; doi:10.3390/ma13071604 www.mdpi.com/journal/materialsMaterials 2020, 13, 1604 biological responses related to bone-to-implant contact by increasing the surface area
Combining the favorable characteristics of microstructural and biological behavioral aspects is a concern related to this range of texturing options [3,4,5], because the literature has shown that some of these methods alter titanium mechanical strength, electrochemical behavior, and bone healing responses [7,8,9,10,11]
The cellular responses of peri-implant bone tissue were compared by considering the sandblasted acid (SLA) and
Summary
Since the use of titanium emerged in the manufacture of medical, dental implants, and osseointegration principles, several modifications to this material have appeared [1,2,3,4,5].These modifications aimed to increase the mechanical resistance and corrosion as well as improve the Materials 2020, 13, 1604; doi:10.3390/ma13071604 www.mdpi.com/journal/materialsMaterials 2020, 13, 1604 biological responses related to bone-to-implant contact by increasing the surface area. Since the use of titanium emerged in the manufacture of medical, dental implants, and osseointegration principles, several modifications to this material have appeared [1,2,3,4,5]. These modifications aimed to increase the mechanical resistance and corrosion as well as improve the Materials 2020, 13, 1604; doi:10.3390/ma13071604 www.mdpi.com/journal/materials. Materials 2020, 13, 1604 biological responses related to bone-to-implant contact by increasing the surface area. Combining the favorable characteristics of microstructural and biological behavioral aspects is a concern related to this range of texturing options [3,4,5], because the literature has shown that some of these methods alter titanium mechanical strength, electrochemical behavior, and bone healing responses [7,8,9,10,11].
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