Abstract

Over the past 3 years we have used oximetry and85krypton to detect and estimate quantitatively the degree of left-to-right shunting in patients with congenital heart disease. The85krypton test is simple and gives excellent differentiation between patients with and without such shunts, and there is no overlap between the two groups. The results of analysis of blood samples taken after breathing the85krypton-air mixture for 10–30 and 30–50 seconds ensures that no shunts are missed. Although oximetry and85krypton results are in good agreement for the quantitation of pulmonary/systemic flow ratios in patients with left-to-right shunts, the best results are probably obtained when the average of data from the 30–50 and 50–70 second inhalation samples are used.

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