Abstract
BackgroundTo describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vasculitis and to compare them to current fluorescein angiography (FA) findings.MethodsThis was an observational case series. Nineteen eyes in 10 patients with retinal vasculitis of various etiologies were imaged with FA (TRC-50DX, Topcon) and OCT-A (SD-OCT, Optovue). The images were reviewed and analyzed.ResultsThe mean age was 36 years (range 24–67 years); there were three males and seven females. The primary vessels involved were veins (89%). Fourteen eyes (74%) had active inflammatory disease during the study period, with signs of vascular sheathing and perivascular leakage on FA. Interestingly, in this group, OCT-A was not able to detect clear signs of active inflammation around the affected vessels. Nevertheless, OCT-A was able to detect secondary lesions in fourteen eyes (74%), including some findings not clearly shown on FA. Most of these were within the macular area. OCT-A was particularly effective in cases of capillary dropout, increased foveal avascular zone, telangiectasias, shunts, and areas of neovascularization.ConclusionFA remains an essential complementary exam for detection of retinal vasculitis. However, OCT-A extends FA findings and affords better assessment of secondary complications.
Highlights
To describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vas‐ culitis and to compare them to current fluorescein angiography (FA) findings
The objective of this study was to compare Optical Coherence Tomography (OCT)-A to the current fluorescein angiography findings in a case series of retinal vasculitis from various etiologies
Secondary complications were seen on OCT-A in fourteen eyes (74%), including some findings not clearly shown on FA
Summary
To describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vas‐ culitis and to compare them to current fluorescein angiography (FA) findings. The characteristic fundoscopic finding is perivascular sheathing that is best demonstrated by vascular staining and leakage on fluorescein angiography (FA) [3]. Various complications can occur, including macular edema, vascular abnormalities, retinal ischemia, retinal. OCT-Angiography (OCT-A) is a new noninvasive diagnostic imaging technique that has recently emerged to assist in the evaluation of chorioretinal diseases. This new technology constructs three-dimensional retinal and choroidal capillary images by Doppler OCT in a matter of seconds, detecting erythrocyte movement in retinal blood vessels, without the use of contrast [5].
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