Comparison between Non-obstructive versus obstructive coronary artery disease patients with acute coronary syndrome

Abstract

Background and aim: Differences in prognosis and baseline clinical presentation have been documented among patient with acute coronary syndrome and coronary artery disease with obstructive (ObCAD) or nonobstructive arteries (NObCAD), but the rates of events largely varied across single studies, the present study aimed to compare the clinical profile, in-hospital and 3-month outcomes major adverse cardiovascular events (MACEs) of Acute Coronary Syndrome (ACS) patients with Non – Obstructive Coronary Diseases (NOCAD), versus Obstructive Coronary Diseases (OCAD). Patients and methods: This prospective observational study included 200 consecutive patients admitted with the diagnosis of ACS to Coronary Care Unit (CCU) at Al- Azhar University hospital Assiut and Sohag Specialized Cardiac and Digestive System Center. Results: There was statistically significant increase in patients suffered from common complication of ACS during 3 months follow up in group B (CAD) than group A (NOCAD).There was statistically significant between number of vessels in both groups with heart failure, and recurrent angina pain complications. Conclusion: Female sex, young age, less diabetic patients, less smoking, less ST segment changes, elevations in peak troponin levels were all associated with coronary angiography showing no significant stenosis.