COMPARISON BETWEEN LEVEL OF INTEREUKIN 10 IN THE GINGIVAL CREVICULAR FLUID AND PERI-IMPLANT SULCULAR FLUID AROUND HEALTHY DENTAL IMPLANTS (SPLIT MOUTH STUDY)

Abstract

INTRODUCTION: Several methods are used in monitoring peri-implant clinical status most of these are periodontal in origin, unfortunately these methods only determine established disease rather than assessing early inflammatory response. Recently, Peri-implant sulcular fluid analysis become a major important index in monitoring peri-implant clinical status.OBJECTIVE: The aim of this study was to compare and evaluate levels of interleukin 10 in the peri-implant sulcular fluid and the gingival crevicular fluid.MATERIALS AND METHODS: Sixteen patients with functionally osseointigrated dental implants were conducted in this split mouth study. Crevicular fluid was collected by absorbent paper points, Interleukin 10 levels were evaluated by using ELISA method for interleukin 10 level from two sites in each subject,study sites: around dental implant and control sites: around antagonist tooth in the same arch. Specimens were evaluated by ELISA method for interleukin level.RESULTS: The levels of IL-10 for neobiotech dental implant showed a mean of 4.45±0.55 in the PISF and 2.85±0.34 GCF and for astratech dental implant IL10 showed a mean of 3.35±0.44 in PISF and 2.75± 0.41 in GCF. Levels of IL10 for the implant systems showed statistically significant higher levels in the PISF than GCF (P<0.05).CONCLUSION: IL-10 can be used as site specific marker in monitoring early inflammatory changes in both gingival crevicular fluid &peri-implant sulcular fluid.