Abstract
Research interest in nanoscale biomaterials has continued to grow in the past few decades, driving the need to form families of nanomaterials grouped by similar physical or chemical properties. Nanotubes have occupied a unique space in this field, primarily due to their high versatility in a wide range of biomedical applications. Although similar in morphology, members of this nanomaterial family widely differ in synthesis methods, mechanical and physiochemical properties, and therapeutic applications. As this field continues to develop, it is important to provide insight into novel biomaterial developments and their overall impact on current technology and therapeutics. In this review, we aim to characterize and compare two members of the nanotube family: carbon nanotubes (CNTs) and janus-base nanotubes (JBNts). While CNTs have been extensively studied for decades, JBNts provide a fresh perspective on many therapeutic modalities bound by the limitations of carbon-based nanomaterials. Herein, we characterize the morphology, synthesis, and applications of CNTs and JBNts to provide a comprehensive comparison between these nanomaterial technologies.
Highlights
Among the current advances in engineering materials, nanotechnology has posed as a promising area of study for the purpose of enhanced drug and gene delivery, among other various applications
Unlike carbon nanotubes (CNTs), there is a lack of rese performed on the stereochemistry of janus-base nanotubes (JBNts); Hemrax et al noted the inherent rality of the twin G^C building blocks of rosette nanotubes (RNTs), as well as the effect of added chiral moie and environmental conditions on the chirality of the nanotubes during synthesis [27] ture studies could further investigate the effects of the nanotube chirality in terms o interaction with their cargo, whether it is a drug or therapeutic gene, or cells within body
There is an obvious disparity between the extent of the research regarding CNTs and the research regarding JBNt, with a more large-scale and comprehensive investigation on the commercially used CNTs
Summary
Among the current advances in engineering materials, nanotechnology has posed as a promising area of study for the purpose of enhanced drug and gene delivery, among other various applications. The symmetry of the structure can be denoted by a set of indices (n,m), which are the graphene unit vectors These vectors are the determining factor for the chiral vector, or the circumference of the tube, as well as the helical angle (χ), which is the angle between the axis of the tube and the. These vectors are the determining factor for the chiral vector, or the circumference of the tube, as well as the helical angle (χ), which is the angle between the axis of the tube and the edge of the graphene lattice [15]. Functionalization entails the addition of an amino acid side chain, or functional group
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