Abstract
Comparison between Fine Needle Aspiration Cytology of Thyroid Nodules and Histology after Surgical Excision
Highlights
Thyroid nodules are extremely common; they are detected in about 4% of the population by palpation and their prevalence rises to as high as 67% when screened by ultrasonography [1,2].Thyroid cancer is rare
Specificity was slightly lower than anticipated based on global data and so did the Positive Predictive Value (PPV) that may be due to the trend of overestimating cellular irregularity, fine needle aspiration biopsy remains an accurate procedure in excluding malignancy due to its high sensitivity and Negative Predictive Value (NPV)
The Bethesda System for Reporting Thyroid Cytology (TBSRTC) is one of the most commonly used systems [9,10,11], and it is adopted by the American Thyroid Association [8]
Summary
Thyroid nodules are extremely common; they are detected in about 4% of the population by palpation and their prevalence rises to as high as 67% when screened by ultrasonography [1,2].Thyroid cancer is rare. Thyroid nodules are extremely common; they are detected in about 4% of the population by palpation and their prevalence rises to as high as 67% when screened by ultrasonography [1,2]. Among all available means used for thyroid nodules management, Fine Needle Aspiration (FNA) biopsy proved to be a safe, inexpensive, uncomplicated procedure that, when handled by an experienced clinician, has a high diagnostic value [5,6,7,8]. Using a proper terminology system for reporting thyroid cytology is essential for achieving the accurate diagnosis and minimizing the false negative and positive rates. Fine Needle Aspiration (FNA) is the gold standard procedure for thyroid nodules diagnosis and management; it helps clinicians to make a proper therapeutic decision and minimizes the need for unnecessary surgery
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