Abstract
This study aimed to compare the efficiency of ultrasound in measuring the size of follicle and urinary Luteinizing Hormone (uLH) kit surge in determining LH surge for determining the time and outcomes of Intra Uterine Insemination (IUI).<strong> </strong>In this comparative, nonrandomized, not blinded clinical trial, 311 IUI cycles in 262 infertile women undergoing IUI were assigned into two groups of ultrasound (n=100 cycles) and uLH kit (n=211 cycles) for the IUI timing. Patients were allowed to choose which study group they preferred. Two weeks after doing the IUI the βhcG was checked and if the chemical pregnancy was confirmed then four weeks after positive chemical pregnancy test the clinical pregnancy was confirmed by observing the fetal heart activity in a pelvic ultrasound. The primary outcome of the study was the comparison of clinical pregnancy rate between two groups.<strong> </strong>The cause of infertility, the average age of men and women, ovulation induction protocol among the two groups was the same. Chemical pregnancy rate did not significantly differ between ultrasound and uLH kit groups (14.3% vs 18.4%, P value=0.11).Moreover, clinical pregnancy rates were similar between ultrasound and uLH kit groups that was not statistically significant (10.3% vs 10.3, P value=0.3). Finally, we concluded that<strong> </strong>the uLH kit is comparable with ultrasonography for timing of IUI. Therefore, the application of uLH kit is superior to ultrasonography in terms of cost and feasibility of use.
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