Comparison Between Efficacy of Triamcinolone Acetonide and Bevacizumab in a Case with Type 2A Idiopathic Parafoveal Telangiectasia

Abstract

Address for Correspondence/Yaz›flma Adresi: Dr. Sabri Raza, Ataturk Training and Research Hospital First Ophthalmology Clinic Bilkent Ankara, Turkey Gsm: +90 507 7 3 8 1 7 97 E-mail: sabri_raza@yahoo.com R e c e i v e d/Gelifl Tarihi: 04.02.2010 A c c e p t e d/Kabul Tarihi 26.10.2010 S u m m a r y P u r p o s e : To compare the efficacy of intravitreal triamcinolone acetonide and bevacizumab in the treatment of a case of type 2A idiopathic parafoveal telangiectasia (IPT). Material and Method: A 55-year-old man with complaint of decreased vision in both eyes was diagnosed as type 2A IPT after a complete ophthalmological examination, fundus fluorescein angiography (FA) and optical coherence tomography (OCT). We injected intravitreally 4 mg /0.1 cc of triamcinolone acetonide into the right eye and 24 hours later 1.25 mg /0.05 cc of bevacizumab into the left eye. The patient was evaluated on the first day, first week, first month, and the third month with FA and OCT. R e s u l t s : Before treatment, best-corrected visual acuity (BCVA) was 5/100 in the right eye and 5/10 in the left eye. At the first-week post-treatment visit, BCVA improved to 5/10 in the right eye and 10/10 in the left eye. On FA, edema in the temporal foveal area was detected in both eyes. This macular edema began to decrease at the first-week visit. Visual acuity was the same on the firstand third-month visits. The FA findings also remained the same. During this 3-month follow-up period, the patient did not need any other additional treatment. D i s c u s s i o n : Intravitreal injections of triamcinolone acetonide and bevacizumab are optional modalities in the treatment of type 2 IPT. The efficacy and permanence of influence-duration of action of triamcinolone acetonide and bevacizumab were similar in our case. (Turk J Ophthalmol 2011; 41: 6-9)