Abstract

Objective To compare the effects between Merogel and expansion sponge in nasal endoscopic dacryocystorhinostomy. Methods Ninty-two cases (104 eyes) of dacryocystitis in the Harbin 242 Hospital from May 2014 to May 2015 were collected and randomly divided into 3 groups.Merogel group contained 31 cases (37 eyes), expansion sponge group contained 34 cases (39 eyes), and the blank control group contained 27 cases (28 eyes). The epiphora, lacrimal situation and regional pain symptoms were observed after the surgery. And then the curative effects, including the cure rate and effective rate, were compared. Results The curative rates of Merogel group and expansion sponge group were 86.5% and 61.5%, respectively, and the difference was statistically significant (P 0.05). The differences in the effective rates between blank control group and Merogel group or expansion sponge group were statistically significant (P 0.05). However, between Merogel group and blank control group, the difference was statistically significant (P<0.05). The curative rate of Merogel group was higher than that of blank control group. Conclusion The anastomotic epithelialization of lacrimal nasal mucosa can be siginificantly improved by using Merogel stoma plasters which can inhibite scar proliferation and granulation tissue formation and increase curative rate of dacryocystorhinostomy with no after-surgery discomfort.It is an effective, safe and efficient biomaterials. Key words: Merogel; Expansion sponge; Dacryocystorhinostomy, nasal endoscopic

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